Based on preliminary studies obtained data of 23 pregnant women, obtained 15 third trimester pregnant women prenatal Massage or pregnancy massage is the application of pressure on the soft tissues of the body,such as skin, muscles,tendons and ligments. Doing prenatal massage is a therapy for reducing back pain in pregnant women, by doing prenatal massage will reduce back pain. purpose of this study was to determine the effect of prenatal massage on reducing back pain in third trimester pregnant women in Midwifery practice Nur Dwi Lesteri Desa Maduretno Blok c1 Karang Bintang District Tanah Bumbu Regency. This research design uses Quasi Experiment with Pre and Post Test Without Control. The samples in this study were 15 trimester III primigravida pregnant women. The study was conducted with the purposive sampling technique. the results of researchers using the Wilcoxon test there are differences in the value of the pre-test most of the respondents are experienced a little more back pain and post-test values for most of the respondents that a number of 7 (46%) experienced back pain as follows pain obtained p value of 0.004 (<0.005). The conclusion of this study is that there is an effect of prenatal massage on the reduction of back pain in trimester III pregnant women. I t is recommended that this prenatal massage be used as an SOP in midwifery care in third trimester pregnant women especially to reduce back pain.